STCS currently has 180 students enrolled for 2010-2011.

STCS originally opened in 1923 as St. Mary's Academic School next to St. Mary of the Angels parish and has remained open continuously since then. In 1998 St. Mary's school was renamed Southern Tier Catholic School when it became a regional school serving all of the Catholic parishes from Cuba to Salamanca to Ellicottville. STCS is now the only remaining Catholic elementary school in the southern tier of western New York between Wellsville to the east and Jamestown to the west.

Curriculum enhanced programs at STCS include the area's only language program for young students. Spanish is taught from Kindergarten through 8th grade. Additionally, the area's only Latin program is offered from 4th through 8th grades.

STCS enjoys a special connection with St. Bonaventure University and its nationally-accredited School of Education. This connection includes discounted educational opportunities for our faculty, tutoring service for our children from SBU's student teachers and access to SBU facilities and programs, including special culture and art programs at the Regina A. Quick Arts Center.

STCS students are taking advantage of the area's Challenger Center for math and science enrichment. The Challenger Center is a NASA-recognized learning program for schoolchildren of all ages, available only in cities that invest and build them. We are fortunate to have one of only 50 available in the United States. Our Challenger Center is located on the campus of St. Bonaventure University and sponsored by two of the area's major employers.